Stem Cells Investigated to Regenerate Damaged Myocardial Tissue:
It has been investigated that damaged myocardial tissues can be regenerated by Embryonic stem cells and Adult stem cells. Embryonic stem cells are pluripotent, they can potentially give rise to the variety of cell types that are involved in regenerating damaged myocardium, including cardiomyocytes, endothelial cells, and smooth muscle cells. Human Embryonic stem cells differentiate into myocytes with the structural and functional properties of cardiomyocytes.
While undifferentiated Embryonic stem cells serve as sources of specific cell used in myocardial repair, quality control should be maintained with respect to the differentiated cells. Differentiated cells that would be used to regenerate heart tissue for transplantation must be purified before. If injected regenerative cells are accidentally contaminated with undifferentiated transplantation cells, a tumor could possibly form as a result of the cell transplant. Purification methodologies continue to improve human Embryonic stem cell differentiation. This apprehension establishes the scientific challenges that accompany the use of all human stem cells. These two things Cell proliferation and differentiation requires basic research on the molecular and genetic signals that regulate cell division and specialization. Once cells have been transplanted, objectionable interactions between the host tissue and the injected cells must be minimum. Those Cells or tissues derived from Embryonic stem cells that are available for use in humans are not tissue-matched to patients and thus would require immunosuppression to limit immune rejection.
Stem cells hold potential as a therapy to regenerate damaged myocardium. Cardiac dysfunction and the limited availability of tissue for cardiac transplantation, stem cells could eventually accomplish a significant need and recover the worth of life for millions of people. Thereby  using these cells will provide clinicians a powerful tool to repair a broken heart.


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